eISSN: 2299-0054
ISSN: 1895-4588
Videosurgery and Other Miniinvasive Techniques
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2/2022
vol. 17
 
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abstract:
Original paper

Laparoscopic splenectomy and esophagogastric devascularization combined with fast-track principles offers greater benefit for patients with portal hypertension

Dong Wang
1
,
Zhang Zhang
1
,
Rui Dong
1
,
Jianguo Lu
1
,
Jikai Yin
1

1.
Department of General Surgery, TangDu Hospital, Fourth Military Medical University, Xi’an, Shannxi Province, China
Videosurgery Miniinv 2022; 17 (2): 326–337
Online publish date: 2022/01/19
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Introduction
Laparoscopic splenectomy and esophagogastric devascularization (LSED) is becoming increasingly popular in the treatment of esophageal-fundic variceal bleeding with portal hypertension (PHT) in China, and its high safety and minimal trauma have been proven. Fast-track (FT) surgery improves patient recovery and decreases postoperative complications. Aim: To determine whether LSED with fast-track principles can provide better outcomes than traditional treatment for patients with PHT.

Material and methods
A total of 140 patients who underwent LSED with either traditional treatment or fast-track principles in our department were retrospectively analyzed. The postoperative outcomes, complications, inflammatory mediators, portal vein thrombosis (PVT) and recurrent esophagogastric variceal bleeding rate were recorded.

Results
No significant differences were found in the patients’ preoperative characteristics. The FT group had better outcomes than the non-FT group with respect to gastrointestinal function recovery, resumption of oral intake, and postoperative hospitalization. The incidence of postoperative complications, including pneumonia, severe ascites, and urinary tract infection, were significantly lower in the FT than the non-FT group. The C-reactive protein and interleukin 6 concentrations and the incidence of PVT were significantly lower in the FT than the non-FT group. The overall recurrent bleeding rate is 11.5% and no significant difference was found between the two groups in the follow-up period.

Conclusions
LSED with fast-track principles was superior to LSED with traditional treatment in terms of postoperative outcomes, complications, postoperative inflammatory reactions, and the incidence of PVT. This strategy is safe and effective for the treatment of PHT.

keywords:

laparoscopic splenectomy, devascularization, portal hypertension, fast-track surgery

  
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