Due to progress in cancer diagnosis and cancer therapies, the population of cancer survivors in Europe is rapidly growing. Cancer survivors have multiple psycho-social needs: loss of fertility and problems in sexuality are two major concerns that, if not adequately treated, may negatively impact survivors’ psychological well-being and prevent the fulfillment of their existential plans, both at the individual and at the interpersonal level. Information and communication regarding these aspects are often neglected in the clinical practice whereas they must be addressed in a regular and systematic manner, and strategies to enhance communication and improve the provision of information should be implemented.