Polish Journal of Pathology
eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
2/2025
vol. 76
 
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Case report

Malignant brain tumour with challenging intraoperative findings

Gabriele Gaggero
1
,
Silvia Bozzano
2
,
Nicoletta Fasano
3
,
Michele D’Agruma
4
,
Valerio GaetanoVellone
1
,
Giulio Fraternali Orcioni
5

  1. Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy
  2. Department of Integrated Surgical and Diagnostic Sciences, Division of Anatomical Pathology, Scuola di Scienze Mediche e Farmaceutiche, Universita di Genova, Genoa, Italy
  3. SSD Neuroradiologia, A.O. Santa Croce e Carle, Cuneo, Italy
  4. SC Neurochirurgia, A.O. Santa Croce e Carle, Cuneo, Italy
  5. SC Anatomia Patologica, A.O. Santa Croce e Carle, Cuneo, Italy
Pol J Pathol 2025; 76 (2): 168-172
Online publish date: 2025/09/22
Article file
- PJP-03056.pdf  [4.74 MB]
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1. WHO Classification of Tumours Editorial Board. Central ner­vous system tumours. 5th ed. IARC, Lyon 2021.
2. Gaggero G, Fraternali Orcioni G, Giordano F, Vellone VG. Glioblastoma, IDH-wildtype, with oligodendrocyte-like cells: a microscopic challenge. Nowotwory J Oncol 2024; 74: 157.
3. Roessler K, Dietrich W, Kitz K. High diagnostic accura­cy of cytological smears of central nervous system tumours. A 15 year experience based on 4172 patients. Acta Cytol 2002; 46: 667-674.
4. Lacruz CR, Catalina-Fernández I, Bardales RH, Pimentel J, López-Presa D, Sáenz-Santamaría J. Intraoperative consulta­tion on pediatric central nervous system tumours by squash cytology. Cancer Cytopathol 2015; 123: 331-346.
5. Georgiu C, Mihut E, Raus I, Mirescu SC, Szabo L, Sovrea AS. Pediatric glioblastoma with giant cells and “supratentori­al” primitive neuroectodermal component – case report and review of the literature. Rom J Morphol Embryol 2015; 56: 1165-1171.
6. Suwala AK, Stichel D, Schrimpf D, et al. Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1. Acta Neuropathol 2021; 142: 179-189.
Copyright: © 2025 Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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