Micro-needling: current state of knowledge and clinical
applications: a review

Agnieszka Ciozda; Ewelina Firlej; Wioleta Kowalska; Magdalena Kwiatkowska; Joanna Bartosińska

doi:10.5114/ada.2025.155419

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

Micro-needling: current state of knowledge and clinical applications: a review

Agnieszka Ciozda

^{1, 2}

,

Ewelina Firlej

¹

,

Wioleta Kowalska

³

,

Magdalena Kwiatkowska

⁴

,

Joanna Bartosińska

¹

Department of Cosmetology and Aesthetic Medicine, Medical University of Lublin, Poland
Doctoral School of Medical University of Lublin, Lublin, Poland
Department of Clinical Immunology, Medical University of Lublin, Poland
Department of Dental Techniques with The Lab of Modern Techniques, Medical University of Lublin, Poland

Adv Dermatol Allergol 2025; XLII (5): 439–443

DOI: https://doi.org/10.5114/ada.2025.155419

Online publish date: 2025/10/20

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Micro-needling mesotherapy is one of the increasingly popular treatments in dermatology clinics due to its wide range of effects on the skin. During the procedure, “micro-channels” are created in the epidermis, which remain open for a short period, allowing for the deeper delivery of selected active substances tailored to the skin’s needs. In addition, micro-needling induces micro-injuries that stimulate the skin’s repair processes, which are essential for tissue regeneration. The aim of the review is to create a practical guide for applying this method in clinical practice. An extensive review of the literature from the past 10 years was conducted using the PubMed database. The database was searched using the following keywords: “micro-needling”, “micro-needle”, “percutaneous collagen induction”, and “dermaroller”. The article is based on previously conducted studies and does not include any new research involving humans or animals.

keywords:

Micro-needling: current state of knowledge and clinical applications: a review

Agnieszka Ciozda 1, 2 , Ewelina Firlej 1 , Wioleta Kowalska 3 , Magdalena Kwiatkowska 4 , Joanna Bartosińska 1

micro-needling, dermal needling, percutaneous collagen induction

Agnieszka Ciozda

^{1, 2}

,

Ewelina Firlej

¹

,

Wioleta Kowalska

³

,

Magdalena Kwiatkowska

⁴

,

Joanna Bartosińska

¹