Polish Journal of Pathology

Abstract

3/2024 vol. 75
Case report

Microinvasive lobular carcinoma arising in a benign phyllodes tumour – a short report and brief review of the literature

  1. St. George’s Hospital, London, United Kingdom
Pol J Pathol 2024; 75 (3): 249-251
Online publish date: 2024/08/08
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Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
Lobular carcinoma in situ (LCIS) with microinvasion is a rare entity which is rarely reported in the literature. We describe a case of microinvasive LCIS following excision of a fibroepithelial lesion. The lesion was graded as U3 and M3 on ultrasonography and mammography respectively, and on core needle biopsy was described as a fibroepithelial lesion with ‘unusual features’. Microscopic examination revealed a fibroepithelial lesion focally colonised by florid E-cadherin negative LCIS with multiple foci of microinvasive classical lobular carcinoma, which lacked a myoepithelial layer on CK5 and S100 staining.
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