eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

without publication fees
2/2020
vol. 71
 
Share:
Send email
Share:
abstract:
Case report

Microscopic extraovarian sex cord proliferation: report of a case with bilateral Fallopian tube involvement and a comprehensive molecular analysis

Pavel Dundr
1
,
Zuzana Věcková
1
,
Ivana Tichá
1
,
Jan Hojný
1
,
Kristýna Němejcová
1
,
Michaela Bártů
1

1.
Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic
Pol J Pathol 2020; 71 (2): 175-180
DOI: https://doi.org/10.5114/pjp.2020.97023
Online publish date: 2020/07/22
View full text Get citation
 
PlumX metrics:
We report a case of a 58-year-old female with microscopic extraovarian sex cord proliferations affecting both Fallopian tubes. Molecular analysis showed likely pathogenic germline missense mutations of the KDM5A and KMT2D genes. However, mutations of other genes, including FOXL2 and STK11, were not detected. Our case represents the 12th case of extraovarian sex cord proliferation reported in the literature to date. This is the first time that a molecular genetic analysis of the lesion has been performed, and it showed a wild-type FOXL2 gene, which represents another argument supporting the estimated benign nature of these rare lesions.
keywords:

extraovarian sex cord stromal proliferation, Fallopian tube, FOXL2
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.