eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
5/2020
vol. 37
 
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abstract:
Review paper

Novel therapies for advanced skin carcinomas

Paulina Modrakowska
1
,
Karolina Balik
1
,
Małgorzata Maj
1
,
Anna Bajek
1

1.
Department of Tissue Engineering, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
Adv Dermatol Allergol 2020; XXXVII (5): 660-670
Online publish date: 2020/11/07
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Advanced skin carcinomas are a serious therapeutic problem. The statistical analysis shows a continuous increase in the incidence of both melanoma and non-melanoma skin cancers. Traditional therapies are characterized by low effectiveness and patients overall survival is not affected by them. By understanding the molecular pathways that lead to the neoplastic transformation and thanks to the knowledge of the immune system, it is possible to use personalized medicine in novel therapies for advanced skin carcinomas.
keywords:

squamous cell carcinoma, basal cell carcinoma, melanoma, targeted therapy, immunotherapy

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