Pediatric Endocrinology Diabetes and Metabolism

Abstract

4/2024 vol. 30
Review paper

Systemic consequences of coeliac disease in children with type 1 diabetes – is it worth following a gluten-free diet?

  1. Department of Pediatric and Adolescent Endocrinology, Chair of Paediatrics, Institute of Paediatrics, Jagiellonian University Medical College, Krakow; University Children’s Hospital in Krakow, Poland
  2. Department of Pediatric and Adolescent Endocrinology, Chair of Paediatrics, Institute of Paediatrics, Faculty of Medicine, Jagiellonian University Medical College, Poland
Pediatr Endocrinol Diabetes Metab 2024; 30 (4): 221-226
Online publish date: 2025/01/27
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Introduction

Coeliac disease (CD) often coexists with type 1 diabetes mellitus (T1D). Children with double diagnosis are frequently asymptomatic, which raises the question of whether to introduce a strict gluten-free diet (GFD) or not.

Aim of the study

To summarise data on systemic consequences of coeliac disease in children with type 1 diabetes mellitus.

Material and methods

The PubMed database was searched for papers to identify meta-analyses, reviews and clinical trials focusing on children.

Results

Coeliac disease, like type 1 diabetes may adversely influence glycaemic control, growth, weight gain, lipid profile and bone health as well as increase the risk of vascular complications. A strict gluten-free diet, at least partly, prevents the development of systemic complications of both disorders.

Conclusions

Dietary restrictions do not have a negative impact on the quality of life of young diabetic patients hence a gluten-free diet with its multifaceted beneficial effects should be recommended to all children with diabetes and coeliac disease.

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