Oral immunotherapy in children for the most common food allergy

Adrianna Kruczkowska; Andrzej Kanturski; Bartosz Tomczyk; Mateusz Wilk; Jakub Ptak; Krzysztof Gomułka

doi:10.5114/ms.2022.119920

eISSN: 2300-6722
ISSN: 1899-1874

Medical Studies/Studia Medyczne

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3/2022
vol. 38

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abstract:

Review paper

Oral immunotherapy in children for the most common food allergy

Adrianna Kruczkowska

¹

,

Andrzej Kanturski

²

,

Bartosz Tomczyk

¹

,

Mateusz Wilk

¹

,

Jakub Ptak

¹

,

Krzysztof Gomułka

³

Student Research Group of Adult Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Group: Krzysztof Gomułka MD, PhD

Faculty of Medicine, University of Opole, Opole, Poland Head of the Faculty: Jacek Jóźwiak PhD

Department of Internal Medicine, Pneumology, and Allergology, Wroclaw Medical University, Wroclaw, Poland Head of the Department: Robert Pawłowicz MD, PhD

Medical Studies/Studia Medyczne 2022; 38 (3): 210–220

DOI: https://doi.org/10.5114/ms.2022.119920

Online publish date: 2022/09/30

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Nowadays, the incidence of food allergies is increasing. While strict allergen avoidance remains the most important therapeutic approach, oral immunotherapy is increasingly being used to desensitize and induce tolerance in children. Oral immunotherapy is a possible treatment for food allergies, which includes the administration of gradually increasing doses of the allergen. While most children can be desensitized, or even gain sustained unresponsiveness, oral immunotherapy involves a high risk of side effects or allergic responses with a need to use epinephrine, and the long-term effectiveness is unknown. In this paper, we summarize recent clinical trials in which oral immunotherapy has been used to treat common food allergies: to cow’s milk, peanuts, and chicken eggs.

keywords:

Oral immunotherapy in children for the most common food allergy

Adrianna Kruczkowska 1 , Andrzej Kanturski 2 , Bartosz Tomczyk 1 , Mateusz Wilk 1 , Jakub Ptak 1 , Krzysztof Gomułka 3

immunotherapy, allergy, desensitization

Adrianna Kruczkowska

¹

,

Andrzej Kanturski

²

,

Bartosz Tomczyk

¹

,

Mateusz Wilk

¹

,

Jakub Ptak

¹

,

Krzysztof Gomułka

³