Dermatology Review
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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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6/2024
vol. 111
 
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abstract:
Case report

Primary Cutaneous Anaplastic Large Cell Lymphoma (PC-ALCL)

Monika Grochowska-Rak
1
,
Katarzyna Kulig
1
,
Magdalena Kacperska-Olborska
2
,
Violetta Karlińska-Jonkisz
1
,
Arleta Grabowska
1

  1. Dermatology Ward, John Paul II Provincial Hospital, Bełchatow, Poland
  2. Patomorphology Department, John Paul II Provincial Hospital, Bełchatow, Poland
Dermatol Rev/Przegl Dermatol 2024, 111, 447-451
DOI: https://doi.org/10.5114/dr.2024.150221
Online publish date: 2025/05/21
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Introduction:
Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is the second most common cutaneous T-cell lymphoma after mycosis fungoides. Clinical correlation with histopathologic features is essential for establishing the diagnosis of primary cutaneous CD30+ T-cell lymphoproliferative disorders. The diagnosis cannot be made based on the pathological presentation alone.

Objective:
To present the characteristic clinical and histopathological features of this rare cutaneous T-cell lymphoproliferative disorder.

Case report:
We present an 83-year-old woman who had been observing multiple, multifocal red-brown nodules with a tendency for necrosis and ulcerations located on the skin of the trunk, upper limbs, and lower limbs. Based on the clinical pathological correlation, primary cutaneous anaplastic large cell lymphoma was diagnosed.

Conclusions:
Clinical examination plays a crucial role in the differential diagnosis of primary cutaneous CD30+ T-cell lymphoproliferative disorders.

keywords:

cutaneous T-cell lymphoma, cutaneous anaplastic large cell lymphoma, CD30+ lymphoproliferative disorder


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