eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
2/2021
vol. 72
 
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abstract:
Short report

Primary angiosarcoma of the vulva: report of a case misdiagnosed as a benign tumor

Simona Stolnicu
1
,
Cristian Podoleanu
2
,
Ildiko Orban
3
,
Octavian Stan
4
,
Bela Szabo
5

1.
Department of Pathology, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania
2.
Department of Cardiology, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania
3.
Department of Pathology, Emergency Hospital, Targu Mures, Romania
4.
Department of Pathology, Emergency County Hospital Sfantu Gheorghe, Romania
5.
Department of Gynecology and Obstetrics, University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, Romania
Pol J Pathol 2021; 72 (2): 167-169
Online publish date: 2021/09/30
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Primary vulvar angiosarcomas have a propensity for varied macroscopic and histologic appearance that initially may not suggest a vascular malignant neoplasm. Therefore, the rarity of the lesion and it’s morphologic diversity may contribute to the high rate of misdiagnosis. We present the case of a 43-year old patient with a primary vulvar lesion, initially misdiagnosed as an angiofibroma. Microscopic examination of the recurrence together with immunohistochemical profile were in favor on a poorly differentiated angiosarcoma. Early diagnoses can improve prognoses in angiosarcomas and, in the case of recurrences, as in the present case, may lead to changes in therapy.
keywords:

primary angiosarcoma, vulva, morphology, immunohistochemistry, management

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