eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
1/2014
vol. 65
 
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abstract:

Primary mucinous cystadenocarcinoma of the breast with amplification of the HER2 gene confirmed by FISH – case report and review of the literature

Betul Bolat Kucukzeybek
,
Seyran Yigit
,
Ayşegul Akder Sari
,
Turkan Rezanko
,
Evren Durak
,
Canan Sadullahoglu

Pol J Pathol 2014; 65 (1): 70-73
Online publish date: 2014/05/13
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Fifty five-years-old woman was presented to the general surgery upon the palpation of a mass in her left breast. In the excisional biopsy performed, partially cystic tumor of 2 × 1 cm with solid areas was macroscopically observed. After through microscopic examination, the patient was diagnosed as invasive mucinous cystadenocarcinoma and the tumor was found to be ER- and PR-negative and C-erbB2 (2+). In the fluorescent in situ hybridization, HER2/neu gene amplification was observed. Here, we present the clinical, cytological, morphological and immunohistochemical features of a very rare type of breast carcinoma, mucinous cystadenocarcinoma of the breast, with the review of the relevant literature.
keywords:

breast, mucinous cystadenocarcinoma, FISH

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