Polish Journal of Pathology

Abstract

4/2025 vol. 76
Case report

Pulmonary granular cell tumor coexisting with interstitial lung disease – a rare case report

  1. Department of Pathology, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
  2. Department of Pathology, Bingol State Hospital, Bingol, Turkey
  3. Department of Pathology, Kanuni Training and Research Hospital, Trabzon, Turkey
  4. Department of Chest Diseases, Karadeniz Technical University Faculty of Medicine, Trabzon, Turkey
  5. Department of Chest Diseases, Ahi Evren Chest Cardiovascular Surgery Training and Research Hospital, Trabzon, Turkey
Pol J Pathol 2025; 76 (4): 338-342
Online publish date: 2026/01/19
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A granular cell tumor (GCT) is a soft tissue neoplasm of rare occurrence in the lung. A 44-year-old male asphalt worker had interstitial lung disease. Incidentally, a 7 mm polypoid nodule was observed at the entrance of the right upper lobe bronchus. Tumor cells were characterized by a large granular eosinophilic cytoplasm and small, uniform nuclei. The neoplastic cells were diffuse positive for S-100, CD-68, NSE, vimentin, and SOX-10, and focal positive for calretinin and inhibin A. This case is unique in its distinction as the second literature case of pulmonary GCT coexisting with interstitial lung disease.
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