Polish Journal of Pathology

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1/2020 vol. 71

Quiz. What is your diagnosis?

  1. Department of Tumor Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Cracow Branch, Poland
  2. Department of Pathology Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
  3. Department of Surgical Oncology, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
  4. Department of Radiology and Imaging Sciences, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
Pol J Pathol 2020; 71 (1): 75-78
Data publikacji online: 2020/05/20
Article file
12-PJP-Quiz_What_is.pdf
Confronting perimenopausal women’s knowledge of coronary heart disease with their health behaviours. Controversial role of hormone replacement therapy in the protection of coronary heart disease
CT scan of the abdominal cavity of a 48-year-old woman revealed extensive thickening of the wall of the pyloric region of the stomach (Fig. 1). During surgery, a gastric tumor was found involving the distal part of the body and the pyloric region of the stomach. The stomach was resected and both macroscopic and histological examination of the surgical specimen showed diffuse neoplastic infiltration covering the full thickness of the stomach wall (Fig. 2) and passing to the surrounding adipose tissue. The tumor texture was built partly of spindle cells forming herring-bone fascicles (Fig. 3), partly of epithelioid cells (Fig. 4, insert) or small round & short spindle cells (Fig. 4). They created hemangiopericytoma-like arrangements (Fig. 5) or formed solid sheets separated by fibrous or myxoid stroma (Fig. 6). Immunohistochemically, tumor cells were characterized by the positive reaction to cytokeratins (AE1/AE3) (Fig. 7), EMA, vimentin (Fig. 8) and Bcl2 antigen (Fig. 9), but did not present reaction against smooth muscle actin, S100 protein, and CD20, HMB45, SOX10, CD31, CD34, CD99 and CD117.
Copyright: © 2020 Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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