eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
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SCImago Journal & Country Rank
3/2020
vol. 71
 
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Quiz
What is your diagnosis?

Paweł Tabakow
1
,
Konrad Kubicki
1
,
Michał Jeleń
2
,
Paweł Gajdzis
3

1.
Department of Neurosurgery, Wroclaw Medical University, Wroclaw, Poland
2.
Department of Immunopathology and Molecular Biology, Wroclaw Medical University, Wroclaw, Poland
3.
Department of Pathomorphology and Oncological Cytology, Wroclaw Medical University, Wroclaw, Poland
Pol J Pathol 2020; 71 (2): 288-290
Online publish date: 2020/10/25
Article file
- PJP-15-Quiz.pdf  [0.37 MB]
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A 12-year-old girl presented with 7 months history of seizures which occurred approximately 2 times per month. The physical examination was unremarkable but magnetic resonance (MR) imaging revealed non-enhancing, superficial mass in the right temporal lobe which measured 2.5 × 1.8 × 2.6cm (Fig. 1). The lesion was hypointense in T1 images, hyperintense in T2 and FLAIR images. Intraoperative consultation specimen was obtained, and squash smear cytology was done. The smears were moderately cellular and consisted of monomorphic cells with fibrillary stroma. The cells were bipolar in shape and showed delicate, elongated projections (Fig. 2). There were quite numerous thin-walled vessels and tumor cells were radially oriented to some blood vessels (Fig. 3). Smears showed also single Rosenthal fibers (Fig. 4). Surgical resection specimen showed grey tumor with brown, cystic area in the center. Histological sections showed glial tumor composed of uniform, bipolar cells with elongated nuclei. The cells showed angiocentric arrangements. Perpendicular orientation of tumor cells to the pia was also noted (Fig. 5). In the center of the tumor there were schwannoma-like areas with structures resembling Verocay bodies (Fig. 6). Mitotic activity, nuclear atypia or necrosis were not found.
Copyright: © 2020 Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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