eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
Current issue Archive Special issues Subscription
SCImago Journal & Country Rank

 
2/2009
vol. 5
 
Share:
Share:
more
 
 
abstract:

REVIEW PAPER
Role of Periodontal Infection in Cardiovascular Disease: A Current Perspective

Jayashree Shanker
,
Vijay V. Kakkar

Arch Med Sci 2009; 5, 2: 125-134
Online publish date: 2009/07/23
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Oral pathogens play a causal role in Cardiovascular Disease (CVD) that is largely driven by inflammation and host immune response. Clinico-epidemiological and animal studies provide a strong link between periodontal disease (PD) and CVD, both of which are highly prevalent, complex disease processes with common risk factors. Genes involved in inflammation, matrix degeneration and immune response have been implicated in the initiation and progression of both diseases. Recent studies have promoted the discovery of novel pathways and lead molecules thus providing opportunities for developing effective vaccine candidates to control disease progression. Following periodontal therapy, studies have shown reduction in the levels of pro-inflammatory cytokines and acute phase reactants, enhancement of endothelial function and lowered risk for future cardiovascular events. The above parallel provides a small yet important handle by which improvement in oral health can open up wider avenues for the overall betterment of systemic health.
keywords:

oral pathogen, peridontal disease, cardiovascular disease, atherosclerosis, stroke

Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe