eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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5/2013
vol. 51
 
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Recommendations for diagnostic and therapeutic procedures in systemic onset juvenile idiopathic arthritis. The opinion of the Panel of Experts of the National Consultant in the field of rheumatology

Zbigniew Żuber
,
Lidia Rutkowska-Sak
,
Elżbieta Smolewska
,
Agnieszka Korobowicz-Markiewicz
,
Katarzyna Kobusińska
,
Bogna Dobrzyniecka
,
Iwona Klimecka
,
Witold Tłustochowicz

Reumatologia 2013; 51, 5: 328-331
Online publish date: 2013/10/31
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Systemic onset juvenile idiopathic arthritis (sJIA) occurs in 10% of patients with juvenile idiopathic arthritis and is manifested by hectic fever, typical rash, systemic symptoms, arthritis and high levels of inflammatory laboratory markers. In some cases of sJIA, response to treatment with standard therapy, including use of biologic medications blocking tumor necrosis factor (TNF), is poor. The efficacy of treatment depends on the rapid implementation of an appropriate therapeutic option. Treatment with interleukin 1 (IL-1) and interleukin 6 (IL-6) blockers is an effective alternative therapy in cases refractory to the most often used therapy.
keywords:

systemic juvenile arthritis, biologic treatment, systemic disease







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