eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
Current issue Archive Manuscripts accepted About the journal Special issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
1/2018
vol. 14
 
Share:
Share:
more
 
 
abstract:
Clinical research

Relationship between urine lipid peroxidation, anthropometric parameters and parameters associated with goitre formation in school-age children

Arkadiusz Zygmunt, Jan Stepniak, Katarzyna Wojciechowska-Durczynska, Kinga Krawczyk-Rusiecka, Andrzej Lewinski, Malgorzata Karbownik-Lewinska

Arch Med Sci 2018; 14, 1: 30–37
Online publish date: 2017/12/19
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction: Oxidative stress has been implicated in the normal ageing process and the pathogenesis of several diseases, including goitre. The aim of the study was to evaluate the relationship between urine lipid peroxidation (LPO) and anthropometric parameters as well as the parameters associated with goitre formation in children.

Material and methods: The subjects included 172 healthy children (93 girls and 79 boys) aged 8–15, divided into 4 age groups – group I (8–9 years), group II (10–11 years), group III (12–13 years) and group IV (14–15 years) – and into 2 groups based on the BSA: the BSA-1 group (≤ 0.55 m2) and the BSA-2 group (> 0.55 m2).

Results: The value of LPO was the highest in group I but the difference between the groups was not statistically significant (p = 0.074). In the BSA-1 group, the LPO was higher than in the BSA-2 group (12.75 ±6.90 nmol/ml and 10.79 ±4.86 nmol/ml, respectively; p = 0.023). We found a weak, negative linear correlation between LPO and age (r = –0.216; p < 0.005), body mass (r = –0.153; p < 0.05), height (r = –0.152; p < 0.05) and BSA (r = –0.151; p < 0.05).

Conclusions: Anthropometric parameters of school-age children independently of age are negatively associated with oxidative damage to membrane lipids, whereas factors promoting goitrogenesis do not contribute to this process.
keywords:

oxidative stress, iodine, thyroid gland

FEATURED PRODUCTS
Quick links
© 2018 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe