eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2021
vol. 38
 
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abstract:
Review paper

Research progress on skin photoaging and oxidative stress

Xi Chen
1
,
Chunsheng Yang
2
,
Guan Jiang
1

1.
Department of Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
2.
Department of Dermatology, the Affiliated Huai’an Hospital of Xuzhou Medical University, the Second People’s Hospital of Huai’an, Huai’an, China
Adv Dermatol Allergol 2021; XXXVIII (6): 931-936
Online publish date: 2022/01/07
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Skin photoaging, which is a kind of exogenous aging, refers to skin elasticity degradation, skin roughening, and wrinkle formation processes because of cascading reactions of a series of kinases after growth factor receptors and cytokine receptors are activated on a cell surface under the UV effect. An extensively recognized skin photoaging mechanism is free radical–oxidative stress concept, proposed by Sohal who represents the authority of the US aging studies. Over the past decade, many new developments in the oxidative stress mechanism have been achieved in terms of the occurrence, development, prevention, and treatment of photodamage.
keywords:

UV, photoaging, oxidative stress, photodamage

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