eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
3/2022
vol. 39
 
Share:
Share:
more
 
 
abstract:
Review paper

Resveratrol in the treatment of asthma based on an animal model

Kamil Leis
1
,
Przemysław Gałązka
1
,
Jakub Kazik
1
,
Tomasz Jamrożek
1
,
Weronika Bereźnicka
1
,
Rafał Czajkowski
2

1.
Department of General and Oncologic Surgery for Children and Adolescents, Chair of Paediatrics, Haematology and Oncology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
2.
Chair of Dermatology and Venerology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
Adv Dermatol Allergol 2022; XXXIX (3): 433-438
Online publish date: 2022/07/15
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Resveratrol is a natural polyphenol found, for example, in red wine, grapes or nuts. One of the resveratrol’s health properties is a cardioprotective activity – it is believed that resveratrol is responsible for the French paradox and anticancer activity. Moreover, the effectiveness of resveratrol in the treatment of asthma is confirmed by multiple research. Resveratrol displays a multiway impact on the reduction of the symptoms of the disease which contributes to the alleviation of inflammation i.a. by: inhibition of cellular infiltration, suppression of oxidative stress, reduction in the volume of mucus, relaxation of smooth muscle, stalling of the fibrosis affecting the respiratory tract or counteracting bronchial hyperresponsiveness. Resveratrol reduces the concentration of eosinophils, pro-inflammatory interleukins and interferes with many signal transduction pathways. In case of concomitance of obesity, resveratrol alleviates the course of asthma. The review juxtaposes the mechanisms of resveratrol activity and presents the results of the published research conducted on rodents.
keywords:

resveratrol, natural polyphenol, asthma treatment

Quick links
© 2022 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.