eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
1/2013
vol. 30
 
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abstract:

Review paper
Centella asiatica in cosmetology

Wiesława Bylka, Paulina Znajdek-Awiżeń, Elżbieta Studzińska-Sroka, Małgorzata Brzezińska

Postep Derm Alergol 2013; XXX, 1: 46-49
Online publish date: 2013/02/20
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Centella asiatica known as Gotu Kola is a medicinal plant that has been used in folk medicine for hundreds of years as well as in scientifically oriented medicine. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecassoside, asiatic and madecassic acids. Centella asiatica is effective in improving treatment of small wounds, hypertrophic wounds as well as burns, psoriasis and scleroderma. The mechanism of action involves promoting fibroblast proliferation and increasing the synthesis of collagen and intracellular fibronectin content and also improvement of the tensile strength of newly formed skin as well as inhibiting the inflammatory phase of hypertrophic scars and keloids. Research results indicate that it can be used in the treatment of photoaging skin, cellulite and striae.
keywords:

Centella asiatica, triterpenes, wound healing, cosmetic preparation

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