eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
3/2012
vol. 29
 
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abstract:

Review paper
Vitamin D impact on immune functions: implications for preventive strategy of allergic disease?

Aleksandra Szczawińska-Popłonyk
,
Anna Bręborowicz

Postep Derm Alergol 2012, XXIX, 3: 176–181
Online publish date: 2012/07/27
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Asthma and allergic diseases are substantial global health problems with a higher prevalence in the westernized countries. It has been proposed that vitamin D deficiency resulting from reduced exposure to sunlight and changes in lifestyle as well as dietary habits may contribute to a high prevalence of asthma and allergic diseases. This review examines the scientific evidence for pluripotent immunoregulatory actions of vitamin D in conjunction with nuclear actions as well as genetic and epigenetic determinants of the vitamin D effects. Findings of epidemiological and clinical studies on the potential association between vitamin D and allergic disease and asthma are reviewed.
keywords:

vitamin D, immunity, asthma, allergy, children

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