eISSN: 2084-9834
ISSN: 0034-6233
Reumatologia/Rheumatology
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4/2016
vol. 54
 
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abstract:
Review paper

Rheumatic diseases induced by drugs and environmental factors: the state-of-the-art – part two

Karolina Niklas
,
Arkadiusz A. Niklas
,
Dominik Majewski
,
Mariusz J. Puszczewicz

Reumatologia 2016; 54, 4: 165–169
Online publish date: 2016/10/05
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The majority of rheumatic diseases belong to the group of autoimmune diseases and are associated with autoantibody production. Their etiology is not fully understood. Certain medications and environmental factors may have an influence on the occurrence of rheumatic diseases. Establishing a cause-effect relationship between a certain factor and disease induction is not always simple. It is important to administer the drug continuously or monitor exposure to a given factor in the period preceding the onset of symptoms. The lack of early diagnosed autoimmune disease, or finally the lack of symptoms within a few weeks/months after discontinuation of the drug/cessation of exposure, is also important.

The most frequently mentioned rheumatic diseases caused by drugs and environmental factors include systemic lupus erythematosus (SLE), scleroderma, systemic vasculitis, polymyositis, dermatomyositis, and Sjögren’s syndrome.

The objective of this study is to summarize current knowledge on rheumatic diseases induced by drugs and environmental factors.
keywords:

rheumatic diseases, drugs, environmental factors







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