eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
3/2021
vol. 38
 
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abstract:
Original paper

Shirazi thyme (Zataria multiflora) extract can alleviate allergic rhinitis: a randomized clinical trial

Nazila Ariaee
1
,
Maryam Panahi
1
,
Mahdi Bakhshaee
2
,
Jalal Ghorbani
1
,
Yalda Ravanshad
3
,
Reza Farid Hosseini
1
,
Alireza Ranjbar
4
,
Farahzad Jabbari
1

1.
Allergy Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2.
Ear, Nose, and Throat Research Center, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
3.
Clinical Research Development Units, Mashhad University of Medical Sciences, Mashhad, Iran
4.
Research Institute of Interventional Allergology and Immunology, Bonn/Cologne, Germany
Adv Dermatol Allergol 2021; XXXVIII (3): 520–525
Online publish date: 2021/07/26
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Introduction
Atopic diseases are global concerns in the today’s industrialized world. Allergic rhinitis is the most common allergic condition affecting 20% of individuals. This disorder is associated with remarkable morbidity and rising healthcare expenditure.

Aim
Considering the anti-inflammatory properties of a plant Zataria multiflora (ZM) with the common name of Shirazi thyme, a randomized clinical trial was designed to evaluate the alleviation of the symptoms of allergic rhinitis.

Material and methods
A total of 30 allergic rhinitis patients were randomly and equally assigned to experimental and control groups. Afterwards, the case group was treated with an extract of ZM and the control group with placebo for 2 months. Finally, the clinical signs and symptoms before and after the treatment according to the SNOT22 questionnaire were analysed.

Results
Comparing the symptoms of allergic rhinitis and an average score of SNOT22 questionnaire between the two groups before the intervention provided some difference, which was significantly greater after the treatment. Based on this questionnaire, our patients in the ZM syrup group had lower grades than before the treatment and experienced amelioration.

Conclusions
Regarding the significant effect of the ZM syrup in reducing symptoms of allergic rhinitis, its use is highly recommended. Since allergic rhinitis is a multifactorial condition, the use of herbal antioxidants along with conventional treatment would result in a more effective improvement of the disease.

keywords:

allergic rhinitis, thyme, Zataria multiflora, herbal product

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