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ISSN: 1233-9687
Polish Journal of Pathology
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vol. 68
Case report

Simultaneous occurrence of pancreatic mixed acinar-ductal adenocarcinoma and primary follicular lymphoma of the duodenum, accompanied by increased number of IgG4 plasma cells in tumor-free parenchyma as concomitant IgG4-related disease or reaction to tumor? A case report

Branislava Ranković
Clara Limbaeck-Stokin
Mihajlo Đokić
Dragoje Stanisavljević
Metka Volavšek

Pol J Pathol 2017; 68 (1): 86-91
Online publish date: 2017/05/23
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Mixed acinar-ductal carcinoma is rare among pancreatic cancers, as is duodenal involvement in follicular lymphoma (FL). Although usually a systemic disease, primary FL of the duodenum occurs, with superficial involvement of the intestinal wall and low risk of progression.

We report on a unique case of mixed ductal-acinar carcinoma of the pancreatic head accompanied by low-grade duodenal FL and autoimmune pancreatitis-like changes in adjacent pancreatic parenchyma.

To our knowledge this is the first report of concomitant pancreatic mixed acinar-ductal carcinoma and duodenal FL. Clinico-pathological features of this unusual case, possible relationship between the entities and differential diagnosis are discussed.

mixed ductal-acinar carcinoma, follicular lymphoma, autoimmune pancreatitis, IgG4, pancreas, duodenum

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