eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
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SCImago Journal & Country Rank
3/2015
vol. 11
 
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abstract:

State of the art paper
Comprehensive assessment of coronary fractional flow reserve

Xiaolong Qi, Guoxin Fan, Deqiu Zhu, Wanrong Ma, Changqing Yang

Arch Med Sci 2015; 11, 3: 483–493
Online publish date: 2015/06/19
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Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive assessment of physiologic stenosis significance and an indispensable tool for decision-making in coronary revascularization. Robust studies have shown that FFR is more effective in accurately identifying which lesions should be stented, and revascularization guided by FFR improves the outcome of coronary artery disease in patients. Therefore, FFR has been upgraded to a class A recommendation in current guidelines when the ischemic potential for specific target lesions is controversial. This article reviews the laboratory practice, functional evaluation of FFR as a gold standard and its emerging clinical application. In addition, novel noninvasive technologies of FFR measurement are discussed in depth.
keywords:

fractional flow reserve, stenosis, revascularization, noninvasive

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