eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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3/2018
vol. 14
 
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Sudden cardiac arrest in the course of Takotsubo syndrome in a 15-year-old girl

Małgorzata Zalewska-Adamiec
,
Hanna Bachórzewska-Gajewska
,
Paweł Kralisz
,
Mariola Tałałaj
,
Mirosław Pryzmont
,
Sławomir Dobrzycki

Adv Interv Cardiol 2018; 14, 3 (53): 318–319
Online publish date: 2018/09/21
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The takotsubo syndrome (TTS) is a transient left ventricular apical contractile dysfunction caused by a stress factor. The clinical manifestation is similar to myocardial infarction. Early and remote prognosis are usually positive, whereas serious complications may occur in the course of TTS, including severe ventricular arrhythmia and cardiac rupture. Generally, TTS occurs in women at 60–80 years of age. However, cases of TTS in several-year-old children and teenagers have also been described [1–3].
A 15-year-old girl with prolapse of the mitral and tricuspid valve flap, with a several-month long medical history of ventricular arrhythmias, lost consciousness while writing a secondary school test. Moreover, her medical history included a stressful, several-month long examination period.
Sudden cardiac arrest (SCA) occurred with the ventricular fibrillation (CF) mechanism and pulseless electrical activity (PEA). Resuscitation actions were undertaken by the school personnel and were continued after 30 min by the Emergency Medical Service. The patient was defibrillated twice. Sudden cardiac arrest occurred again during transport to the Intensive Care Unit (ICU) of the Children’s Hospital.
On admission to the ICU, ECG demonstrated sinus tachycardia 130/min and ST elevation in V2–V6 leads. The laboratory test showed an increased troponin level – 3.464 ng/ml. Following hemodynamic stabilization of the patient and cardiological consultation, the patient was subjected to coronarography. Examination revealed normal coronary arteries, whereas the concomitant ventriculography revealed extensive left ventricular contractility disorders typical of the Takotsubo syndrome, with ejection fraction (LVEF) 25% (Figure 1). Despite the intensive therapy, the patient remained unconscious during subsequent hospitalization and was subjected to respirator treatment. Symptoms of serious central nervous system (CNS) damage were neurologically determined.
On day 10 of hospitalization follow-up echocardiography was performed, showing resolution of contractility disorders, and LVEF was estimated at 60% (confirmation of TTS). Brain scintigraphy was performed, and revealed absence of brain tissue perfusion. On day 18 of hospitalization brain death was pronounced, and upon the parents’ consent organs were removed.
According to the literature, TTS is typically caused in small children and teenagers by a physical factor (secondary TTS), whereas in...


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