Pilomatrixoma is a benign subcutaneous tumour originating from sebaceous glands, typically measuring 1-5 cm in size, while if exceeding 5 cm in diameter it is named a giant pilomatrixoma. Warthin tumour (WT) also known as papillary cystadenoma lymphomatosum is the second most common benign tumour of the parotid gland. We present the patient with a rare condition of two synchronous tumours: giant pilomatrixoma in the submandibular region and Warthin tumour in the parotid gland. Our objective was to alert otolaryngologists to the presence of multiple tumours as well as a correct differential diagnosis of lesions occurring in the head and neck area.