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ISSN: 1233-9687
Polish Journal of Pathology
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2/2020
vol. 71
 
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abstract:
Case report

Synovial sarcoma of the stomach: case report and systematic review of the literature

Martyna Kurpińska
1
,
Ewa Kaznowska
2
,
Anna Kruczak
1
,
Katarzyna Mularz
1
,
Agnieszka Adamczyk
1
,
Jarosław Długosz
3
,
Józef Gancarz
4
,
Janusz Ryś
1

1.
Department of Tumor Pathology, Maria Sklodowska-Curie National Research Institute of Oncology, Krakow Branch, Poland
2.
Department of Pathology Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
3.
Department of Surgical Oncology, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
4.
Department of Radiology and Imaging Sciences, Specialist Hospital, Podkarpacki Oncology Center in Brzozow, Poland
Pol J Pathol 2020; 71 (2): 181-193
DOI: https://doi.org/10.5114/pjp.2020.97024
Online publish date: 2020/07/22
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Synovial sarcoma is a rare mesenchymal malignant neoplasm that presents a specific t(X;18) translocation forming SS18(SYT)-SSX chimera gene. It is most commonly seen in soft tissues of the extremities. The digestive tract is an exceptional site of involvement. We report a case of primary gastric synovial sarcoma in a 48-year-old female. Differential diagnosis of synovial sarcoma from other spindle cell, mesenchymal and cytokeratin-positive tumors is critical for the treatment and prognosis. Immunohistochemistry studies and molecular analysis are required to settle a proper diagnosis.
keywords:

synovial sarcoma, stomach, spindle cell neoplasm, cytokeratin
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