eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
Current issue Archive Manuscripts accepted About the journal Editorial board Journal's reviewers Abstracting and indexing Subscription Contact Instructions for authors
SCImago Journal & Country Rank
5/2020
vol. 37
 
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abstract:
Review paper

The microbiome and its impact on food allergy and atopic dermatitis in children

Ewa Łoś-Rychalska
1
,
Marcin Gołębiewski
2, 3
,
Tomasz Grzybowski
4
,
Urszula Rogalla-Ładniak
4
,
Aneta Krogulska
1

1.
Department of Paediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
2.
Interdisciplinary Centre of Modern Technologies, Nicolaus Copernicus University, Torun, Poland
3.
Chair of Plant Physiology and Biotechnology, Nicolaus Copernicus University, Torun, Poland
4.
Chair of Forensic Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland
Adv Dermatol Allergol 2020; XXXVII (5): 641-650
Online publish date: 2020/11/07
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Food allergy (FA) affects 4–10% of children, especially children with atopic dermatitis (AD). During infancy the gut microbiome may determine both the course of FA and tolerance to food allergens. Analogically, the skin microbiome changes in the course of AD. Most studies have associated FA with a lower abundance and diversity of Lactobacillales and Clostridiales, but greater numbers of Enterobacterales, while AD in children has been associated with lower numbers of Staphylococcus epidermidis and S. hominis but an abundance of S. aureus and Streptococcus species. An understanding of the impact of the microbiome on the clinical course of FA and AD may allow for the development of new models of allergy treatment and prevention.
keywords:

microbiome, food allergy, atopic dermatitis, infants

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