Treatment with metformin in induction of ovulation and in treatment of imminent abortion in womenwith polycystic ovary syndrom (PCOS)

Piotr Skałba; Wojciech Szanecki

ISSN: 1231-6407

Ginekologia Praktyczna - - - ARCHIVAL

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5/2005
vol. 13

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abstract:

Treatment with metformin in induction of ovulation and in treatment of imminent abortion in womenwith polycystic ovary syndrom (PCOS)

Piotr Skałba

,

Wojciech Szanecki

Gin Prakt 2005; 86, 5: 2-5

Online publish date: 2005/12/12

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Polycystic ovary syndrom (PCOS) is common endocrinological disorder affected large group women of reproductive age. Patogenesis of this syndrom is rather unknown. Insulin resistance accompanies very often with PCOS. Hormonal disturbances in PCOS lead to menstruation disorders, infertility and spontaneous abortion. Treatment with insulin sensitisers improves clinical pattern of women with PCOS specially treatment of infertility. Metformin reduces insulin, insulin resistance, insulin secretion, weight, testosterone and development of gestational diabetes, increases the ovulatory rate and pregnancy rate. The recent studies show beneficial effects of using metformin for women with PCOS treated during their pregnancy.

keywords:

Treatment with metformin in induction of ovulation and in treatment of imminent abortion in womenwith polycystic ovary syndrom (PCOS)

Piotr Skałba , Wojciech Szanecki

polycystic ovarian syndrom, metformin, insulin resistance, imminent abortion, infertility

Piotr Skałba

,

Wojciech Szanecki