eISSN: 1896-9151
ISSN: 1734-1922
Archives of Medical Science
Current issue Archive Manuscripts accepted About the journal Special issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
1/2020
vol. 16
 
Share:
Share:
more
 
 
abstract:
Clinical research

Triiodothyronine levels were positively correlated with opening of collateral circulation in cerebral infarction patients with large artery atherosclerosis

Xiao-Feng Dong
,
Fan-Zhen Kong
,
Ming-Qiang Shen
,
Jiang Huang
,
Zong-En Gao
,
Qian-Zhu Guo
,
Zhong Zhao
,
Wei-Feng Luo
,
Qing-Zhang Cheng
,
Guan-Hui Wu

Arch Med Sci 2020; 16 (1): 51–57
Online publish date: 2019/12/31
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
Non-thyroidal illness syndrome (NTIS) is one of the signs for poor prognosis of cerebral infarction (CI), but its risk factors had never been explored. In this study, we analyzed the potential effect of collateral circulation on prognosis prediction of triiodothyronine for large artery atherosclerosis cerebral infarction (LAA-CI) patients.

Material and methods
Clinical data of CI patients between 2012 and 2014 were collected. Imaging inspection was used for determining TOAST classification and evaluating collateral circulation. One-year follow-up was conducted for mRS score by telephone.

Results
T3 level in the NTIS group (p = 0.001) was significantly decreased while TSH level (p < 0.001) was increased. Patients in the NTIS group had a poorer prognosis (p = 0.008) and the main reason was the high mortality (p = 0.002). NTIS predicted poor collateral circulation (p = 0.026) and good collateral circulation tended to be less likely concomitant with NTIS (p = 0.001). Logistic regression analysis showed that triiodothyronine concentrations (OR = 4.760, 95% CI: 1.981–11.456, p < 0.001) were positively correlated with but advanced age (OR = 0.756, 95% CI: 0.645–0.886, p = 0.001) negatively with opening of collateral circulation.

Conclusions
Poor opening of collateral circulation was likely to mediate the prediction of NTIS for prognosis of LAA-CI patients.

keywords:

cerebral infarction, non-thyroidal illness syndrome, collateral circulation, prognosis

Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe