eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
4/2021
vol. 38
 
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abstract:
Letter to the Editor

Unusual clinical picture of food-dependent exercise-induced anaphylaxis associated with soybean allergy and a reverse sequence of causative factors

Anna Radlińska
1
,
Krzysztof Gomułka
1
,
Anna Zaleska
1
,
Wojciech Mędrala
1

1.
Department of Internal Medicine, Pneumonology and Allergology, Wroclaw Medical University, Wroclaw, Poland
Adv Dermatol Allergol 2021; XXXVIII (4): 703-705
Online publish date: 2021/09/24
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Food-dependent, exercise-induced anaphylaxis (FDEIA) is a distinct form of food allergy associated with anaphylaxis, in which clinical symptoms are elicited only when two factors coexist – intake of sensitizing food with subsequent physical exertion. It was first described by Maulitz et al. in 1979 [1]. The pathomechanism of FDEIA remains to be the subject of research, especially the relevance of physical exertion in the elicitation of IgE-mediated systemic allergic reaction [2]. Most patients experience their symptoms after postprandial exercise (the typical sequence) [3]. Our team was the first who presented the case of FDEIA with atypical episodes when anaphylaxis occurred after exercise, followed by ingestion of the sensitizing allergen [4].
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