Abstract
Xanthogranuloma necrobioticum in the course of monoclonal gammopathy of undetermined significance and idiopathic neutropenia
- Dermatology Student Scientific Association at the Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Dermatologiczne Studenckie Koło Naukowe przy Katedrze i Klinice Dermatologii, Wenerologii i Alergologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
- Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Klinika Dermatologii, Wenerologii i Alergologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
- Department of Hematology and Transplantology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Klinika Hematologii i Transplantologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
- Department of Pathomorphology, Faculty of Medicine, Medical University of Gdansk, Gdansk, Poland; Katedra i Zakład Patomorfologii, Wydział Lekarski, Gdański Uniwersytet Medyczny, Gdańsk, Polska
- Department of Pathomorphology and Forensics, Collegium Medicum, Medical Faculty, Warmia and Mazury University, Olsztyn, Poland; Katedra Patomorfologii i Medycyny Sądowej, Collegium Medicum, Wydział Lekarski, Uniwersytet Warmińsko-Mazurski, Olsztyn, Polska
Introduction:
Xanthogranuloma necrobioticum is a rare, chronic granulomatous disease manifested by the presence of papules and yellowish nodules, most often located in the orbital area. Because of its rarity, the diagnosis and treatment of this dermatosis may be difficult, therefore, the authors found presentation of a case purposeful.
Case report:
A case of a 57-year-old male with xanthogranuloma necrobioticum coexisting with monoclonal gammopathy of undetermined significance and neutropenia of undetermined etiology is presented.
Conclusions:
Patients diagnosed with xanthogranuloma necrobioticum should be under long-term observation considering the possibility of co-occurrence of a hematological disease. Achieving therapeutic efficacy may be difficult and requires a complex therapeutic strategy.
Keywords
xanthogranuloma necrobioticum, monoclonal gammopathy, neutropenia, triamcinolone acetate, intravenous immunoglobulin preparations
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