@Article{Banaszkiewicz2008,
journal="Pielęgniarstwo Chirurgiczne i Angiologiczne/Surgical and Vascular Nursing",
issn="1897-3116",
volume="2",
number="1",
year="2008",
title="Usefulness of faecal occult blood testing (FOBT) applied to preventive and diagnostic schedule in hereditary non-polyposis colorectal cancer (HNPCC) family members",
abstract="  Background:  HNPCC family members require special diagnostic and preventive treatment. Despite the colonoscopic examination at one-to-two-year intervals applied to these patients starting from their early twenties (20-25 years of age), still a certain number of new cases of advanced colorectal malignancy can be found.        Aim of the study: The aim of this study was to analyse whether Hem-Check-1, an immunochromatographic faecal blood test applied to HNPCC family members additionally to standard endoscopic treatment, can be of help in earlier diagnosis of advanced colorectal cancer (CRC).   Material and methods:  Investigations were carried out in a group of 56 consecutive HNPCC family members of whom 41 were female (73.23%) and 15 were male patients (26.77%). FOBT and colonoscopy were applied to each patient. 17 patients presented positive on endoscopic evaluation (30.36%). Next sensitivity, specificity, both positive and negative predictive values and accuracy of Hem-Check-1 testing towards advanced CRC were calculated.    Results:  Advanced CRC was diagnosed in 7 patients. Hem-Check-1 values were as follows: sensitivity (85.71%), specificity (91.84%), positive predictive value (60%), negative predictive value (97.83%) and accuracy of the test (91.07%).    Conclusion:  FOBT may be effective in qualifying HNPCC family members for earlier endoscopic work-up.",
author="Banaszkiewicz, Zbigniew
and Tojek, Krzysztof
and Jarmocik, Paweł
and Lubinski, Jan
and Jawień, Arkadiusz",
pages="1--4",
url="https://www.termedia.pl/Usefulness-of-faecal-occult-blood-testing-FOBT-applied-to-preventive-and-diagnostic-schedule-in-hereditary-non-polyposis-colorectal-cancer-HNPCC-family-members,50,10145,1,1.html"
}