@Article{Trojnarska2008,
journal="Archives of Medical Science",
issn="1734-1922",
volume="4",
number="3",
year="2008",
title="Clinical researchB-type natriuretic peptide level in adult patients after successful repair of coarctation of the aorta",
abstract="  Introduction:  The aim of the study was to evaluate BNP in adults after successful surgery of CoAo.   Material and methods:  Seventy-four patients after surgery of CoAo entered the study group aged 31.2\±9.8 and operated at age 10.4\±6.8. The control group consisted of 30 healthy volunteers (18 males) aged 32.2\±6.6. 2D and Doppler echocardiography was performed. Patients were divided into two groups: with or without DAo restenosis. All patients underwent an exercise treadmill test. Patients were enrolled in the study if they were found to have untreated HT or if a two-week cessation of hypotensive therapy was possible. In all cases BNP level was measured.   Results:  32 patients showed normal BP while 10 had exercise-induced HT. The remaining patients had chronic HT. The maximal systolic gradient in DAo was comparable in all groups. In 33 patients residual DAo stenosis was noted (DAo+) 36.6\±9.8 mm Hg, and in another 41 it was not (DAo\–) 15.9\±5.1. The maximal transvalvular aortic pressure gradient was 11.7\±6.2 mm Hg. BNP in the study group was higher than among controls, though it was higher in the DAo+ subgroup than in the DAo\– subgroup. BNP level also correlated with patients\’ age at the time of operation (R=0.275, P=0.02), and with transaortic gradient (R=0.233, P=0.04).   Conclusions:  BNP in adults after CoAo repair is significantly elevated, which may be due to the pressure load of LV.",
author="Trojnarska, Olga
and Bręborowicz, Piotr
and Gwizdała, Adrian
and Pyda, Małgorzata
and Oko-Sarnowska, Zofia
and Szyszka, Andrzej
and Grajek, Stefan",
pages="274--277",
url="https://www.termedia.pl/Clinical-research-B-type-natriuretic-peptide-level-in-adult-patients-after-successful-repair-of-coarctation-of-the-aorta,19,11199,1,1.html"
}