@Article{Kula2008,
journal="Gastroenterology Review/Przegląd Gastroenterologiczny",
issn="1895-5770",
volume="3",
number="5",
year="2008",
title="Initial evaluation of PET/CT imaging in patients with gastrointestinal stromal tumour",
abstract="  Introduction:  Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastrointestinal tract. Combined positron emission tomography using 18F-fluorodeoxyglucose (FDG) and computed tomography (PET/CT) is one of the most modern imaging methods in patients with GIST.   Aim:  To perform a retrospective analysis of the clinical value of PET/CT imaging in patients with GIST after surgical treatment and/or chemotherapy.   Material and methods:  PET/CT examinations were performed in 20 patients with GIST \– 10 women and 10 men aged from 18 to 73 years (mean 52.1). The primary sites of the tumour were: ileum \– 12, stomach \– 5, mesentery \– 2, duodenum \– 1. The PET/CT was performed with a Biograph LSO Siemens 60-90 min after the intravenous administration of 5 MBq/kg FDG. In 2 patients PET/CT was repeated after treatment with a tyrosine kinase inhibitor.   Results:  PET/CT imaging presented focal lesions with increased FDG metabolism in 9 patients. All the diagnoses were true positive. The results were true negative in the remaining 11 patients. In one patient PET/CT diagnosed tumour response to tyrosine kinase inhibitor therapy, in the other case no response.   Conclusions:  PET/CT imaging may have significant clinical value in the diagnosis of postoperative recurrence of GIST after surgical treatment. This method is a useful modality to monitor treatment response to tyrosine kinase inhibitor in patients with GIST. This modality has the potential to influence clinical decision making.",
author="Kula, Zbigniew
and Małkowski, Bogdan
and Pietrzak, Tomasz
and Szefer, Jarosław",
pages="255--261",
url="https://www.termedia.pl/Initial-evaluation-of-PET-CT-imaging-in-patients-with-gastrointestinal-stromal-tumour,41,11303,1,1.html"
}