@Article{Kisiel2009,
journal="Contemporary Oncology/Współczesna Onkologia",
issn="1428-2526",
volume="13",
number="3",
year="2009",
title="Acute myeloid leukaemia in a patient with AIDS \– case report",
abstract="HIV-infected subjects are at increased risk of developing several cancers. Three of them \– Kaposi\’s sarcoma, non-Hodgkin\’s lymphoma and invasive cervical cancer \– are accepted as AIDS-defining malignancies. Acute myeloproliferative diseases are rare in HIV-infected individuals. HIV-seropositive patients with acute myeloid leukaemia (AML) are presented in the literature as isolated case reports. We describe a case of acute myeloid leukaemia (FAB-M5a) with Kaposi\’s sarcoma occurring in a HIV/EBV coinfected woman, sequentially treated with highly active antiretroviral therapy (ARV). She received treatment with a standard AML induction regimen consisting of infusion of cytarabine 200 mg/m 2  daily for 5 days, etoposide 100 mg daily for 5 days and idarubicin 10 mg/m 2  daily for 3 days, followed by double consolidation chemotherapy (I \– cytarabine + mitoxantrone, II HD cytarabine). Complete remission (CR) lasting six months was achieved. HIV viral load increase was not observed. CD4+ cell count has remained above 200/\µl. ARV has resulted in a significant decline of mortality and opportunistic infections, improving overall survival among HIV-infected patients. Conventional chemotherapy regimens often followed by haematopoietic stem cell transplantation have become commonly used. As acute myeloid leukaemia is rare in HIV-infected individuals, recommendations on treatment have not been defined and each case is treated individually.",
author="Kisiel, Elżbieta
and Centkowski, Piotr
and Warzocha, Krzysztof
and Podlasin, Regina B.",
pages="144--149",
url="https://www.termedia.pl/Acute-myeloid-leukaemia-in-a-patient-with-AIDS-8211-case-report,3,12896,1,1.html"
}