@Article{Kłopotowski2009,
journal="Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej",
issn="1734-9338",
volume="5",
number="3",
year="2009",
title="Original paper Local ultrasound-guided thrombin injection for treatment  of post-catheterization femoral artery pseudoaneurysm  \– a short term follow-up",
abstract=" Background:   Femoral artery false aneurysms are a relatively common complication after cardiac catheterization. The majority of small pseudoaneurysms undergo spontaneous occlusion but larger ones usually require treatment.    Aim:   To prospectively evaluate the efficacy and safety of percutaneous ultrasound \– guided thrombin injection (UGTI) in the management of femoral artery pseudoaneurysms.   Methods:   One hundred and eighty six consecutive patients (95 female, age 64.8 \± 11.3 years) with post-catheterization femoral artery pseudoaneurysm were treated with ultrasound-guided local thrombin injection. At the time of diagnosis 39 (21%) patients were receiving anticoagulation therapy, 103 (55.4%) antiplatelet therapy only, and 44 (23.6%) both types of therapy.    Results:   A single-chamber pseudoaneurysm was diagnosed in 145 (78%) patients and complex pseudoaneurysm in 41 (22%). A total number of 198 thrombin injection was performed: 1.04 injection per patient with single-chamber pseudoaneurysm and 1.12 injections per patient with complex pseudoaneurym. The mean dose of injected bovine thrombin was 620 IU. UGTI was primarily successful in 175 of 186 patients (94%): in 139 (95.9%) patients with single-chamber and in 36 (87.8%) patients with complex pseudoaneurysms (p = 0.07). Including a second attempt the success rate was 143 (98.6%) patients for single-chamber and 40 (97.6%) patients for complex pseudoaneurysm (p = 0.52). In addition, one single-chamber pseudoaneurysm was obliterated after a third injection. Overall, the treated pseudoaneurysms were completely occluded in 184 (98.9%) patients. Final success rate did not differ between patients with single-chamber and complex pseudoaneurysms (99.3 vs. 97.6%, p = 0.39, respectively). Two major complications occurred: a symptomatic peripheral thrombosis and an episode of loss of consciousness.    Conclusions:   Ultrasound guided occlusion of iatrogenic femoral artery pseudoaneurysms using thrombin injection is an efficacious and safe procedure.",
author="Kłopotowski, Mariusz
and Kukuła, Krzysztof
and Mączyńska, Renata
and Dąbrowski, Maciej
and Kępka, Cezary
and Zieliński, Tomasz
and Rywik, Tomasz
and Leszek, Przemysław
and Pręgowska-Chwała, Barbara
and Michael-Rowicka, Katarzyna
and Rynkun, Dariusz
and Witkowski, Adam
and Rużyłło, Witold",
pages="129--136",
url="https://www.termedia.pl/Original-paper-Local-ultrasound-guided-thrombin-injection-for-treatment-of-post-catheterization-femoral-artery-pseudoaneurysm-8211-a-short-term-follow-up,35,13601,1,1.html"
}