@Article{Vicini2010,
journal="Journal of Contemporary Brachytherapy",
issn="1689-832X",
volume="2",
number="1",
year="2010",
title="Clinical InvestigationsDosimetric Improvements in Balloon Based Brachytherapy Using the Contura\® Multi-Lumen Balloon (MLB) Catheter to Deliver Accelerated Partial Breast Irradiation",
abstract="  Purpose:  Preliminary dosimetric findings in patients managed with the Contura\&reg; Multi-Lumen Balloon (MLB) breast brachytherapy catheter to deliver accelerated partial breast irradiation (APBI) on a multi-institutional phase IV registry trial were reviewed.    Material and methods:   CT-based 3D planning with dose optimization was performed for all patients. For the study, new ideal dosimetric goals were developed: 1) \&#8805; 95% of the prescribed dose (PD) covering \&#8805; 90% of the target volume (TV), 2) a maximum skin dose \&#8804; 125% of the PD, 3) maximum rib dose \&#8804; 145% of the PD, and 4) the V150 \&#8804; 50 cc and V200 \&#8804; 10 cc. The frequency of concurrently achieving these dosimetric goals using the Contura\&reg; MLB was investigated.    Results:   194 cases were evaluable. Employing the MLB, all ideal dosimetric criteria were achieved in 76% of cases. Evaluating dosimetric criteria separately, 90% and 89% of cases met the new ideal skin and rib dose criteria, respectively. In 96%, ideal TV coverage goals were achieved and in 96%, dose homogeneity criteria (V150 and V200) were met. For skin spacing \&#8805; 5-7 mm, the median skin dose was 121% of the PD and when < 5 mm, the median skin dose was 124.4%. For rib distancees < 5 mm, the median rib dose was reduced to 136.4% of the PD. For skin spacing < 7 mm and distance to rib < 5 mm, the median skin and rib doses were concurrently limited to 121% and 142.8% of the PD, respectively.    Conclusions:   The Contura\&reg; MLB catheter provides potential improvements in dosimetric capabilities (i.e., reduced skin and rib doses and improved TV coverage) in many clinical scenarios.",
author="Vicini, Frank A
and Douglas, Arthur
and Todor, Dorin
and Julian, Thomas
and Lyden, Maureen",
pages="1--8",
doi="10.5114/jcb.2010.13716",
url="http://dx.doi.org/10.5114/jcb.2010.13716"
}