@Article{Gordon2010,
journal="Archives of Medical Science",
issn="1734-1922",
volume="6",
number="5",
year="2010",
title="Clinical researchDyslipidaemia in hypertensive obese type 2 diabetic patients in Jamaica",
abstract="  Introduction  : Hypertension and obesity are common problems among diabetic patients accelerating progression of vascular diabetic complications.       Material and methods  : A two-stage stratified random sampling design was used, and individuals aged 15 years and over were interviewed. This cross-sectional study evaluated lipid abnormalities of 117 obese type 2 diabetic patients  (28 males and 89 females), and 56 hypertensive obese type 2 diabetic patients (22 males and 34 females). Total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C) and high-density lipoprotein cholesterol (HDL-C) concentrations were assayed using standard biochemical methods.       Results  : Hypertensive obese type 2 diabetic females had significantly higher mean serum concentrations of TC (p = 0.043), TG (p = 0.046), LDL-C (p = 0.040), TC/HDL-C ratio (p = 0.001) and LDL-C/HDL-C ratio (p = 0.003) compared with hypertensive obese non-diabetic females. Similar results were found in hypertensive obese type 2 diabetic males compared with hypertensive obese non-diabetic males. Hypertensive obese type 2 diabetic females had significantly higher serum TC, TG and TC/HDL-C ratio (p < 0.05) than hypertensive obese type 2 diabetic males. Hypertensive obese type 2 diabetic females had significantly higher mean serum concentrations of TG (p = 0.03) and TC  (p = 0.01) than obese type 2 diabetic females. There was a significant association between blood glucose and LDL-C concentrations in type 2 diabetic subjects  (r = 0.36; p < 0.05).      Conclusion  : Obese hypertensive type 2 diabetic females are exposed more profoundly to risk factors including atherogenic dyslipidaemia compared with males.",
author="Gordon, Lorenzo
and Ragoobirsingh, Dalip
and Morrison, Errol
and McGrowder, Donovan
and Choo-Kang, Eric
and Martorell, E.",
pages="701--708",
doi="10.5114/aoms.2010.17084",
url="http://dx.doi.org/10.5114/aoms.2010.17084"
}