@Article{Gao2010,
journal="Archives of Medical Science",
issn="1734-1922",
volume="6",
number="5",
year="2010",
title="Clinical researchA survey on the distribution of healthy people with different anti-tumour ability",
abstract="  Introduction  : The aim of the study was to explore the distribution of healthy people with different anti-tumour ability.    Material and methods  : Leukocytes were separated by the Ficoll-Hypaque density gradient centrifugal method. Then they were mixed with A549, MCF-7 and Hela cells at different ratios. The survival rate for target cells was observed and counted by Fluoroskan. Immune function for 200 healthy people was analysed by flow cytometry.     Results  : The results obtained by confocal microscopy revealed that human blood leukocytes possessed direct anti-tumour activity. The survival rate for tumour cells was the lowest in the condition of 20:1 ratio of effector cells to target cells. We speculated that in 200 healthy people the leukocyte capacity for killing MCF-7 cells is stronger than the leukocyte capacity for killing A549 cells and Hela  cells. We also found that the distribution for 200 healthy people with different anti-tumour ability was different for different tumour cells. The number of healthy people with the strongest anti-tumour ability was highest when the target cells were MCF-7 cells. Moreover, the survival of A549, MCF-7 and Hela cells was correlated with T, B and NK lymphocytes.     Conclusions  : From the above, we can select healthy individuals with strong anti-tumour ability as anti-tumour donors according to their distribution with different anti-tumour ability, which opened up a new direction for fighting human cancer.",
author="Gao, Yanhong
and Xu, Xiaolan
and Dong, Zhennan
and Jiang, Chaoguang
and Gao, Jin
and Hu, Jinchuan
and Gui, Junhao
and Wang, Haibao
and Tian, Yaping",
pages="806--814",
doi="10.5114/aoms.2010.17099",
url="http://dx.doi.org/10.5114/aoms.2010.17099"
}