@Article{Gottwald2011,
journal="Medycyna Paliatywna/Palliative Medicine",
issn="2081-0016",
volume="3",
number="1",
year="2011",
title="Bone metastases from breast cancer – analysis of 63 cases",
abstract=" Objectives : Breast cancer is the most common malignant neoplasm in women. In metastatic disease bones are often involved.     The aim of the study : was to investigate the clinical feature in patients with breast cancer metastasized to bones.     Material and methods : Sixty-three patients were studied retrospectively. Clinical and pathologic data were analyzed. The time from primary diagnosis until the relapse in bones was evaluated. Metastatic tumors in bones were characterized.     Results : At the diagnosis of primary cancer the patients aged 34-70 years old (54.0 ±8.7). The histology of the cancer was ductal adenocarcinoma (85.7%) and lobular adenocarcinoma (14.3%).  The interval from diagnosis of primary cancer until the relapse in bones was 0-216 months  (52.1 ±60.5). Bone metastases were less often solitary (25.4%) than multifocal (74.6%). In 47.6% metastatic tumors were diagnosed only in bones, and 52.4% of patients had additional metastases. The synchronous metastases were located most commonly in central nervous system, liver and lungs. The treatment of relapse in bones was in 6.4% surgery followed by radiotherapy, in 73% of patients radiotherapy alone and in 20.6% only palliative care.     Conclusions : The development of brain metastases occurs commonly in patients aged over 60 years old. Bone metastases are in most cases multifocal, and in near 50% of patients synchronous extra­osseous metastases develop. The oncologic treatment of choice in bone metastases from breast cancer remain palliative radiotherapy.",
author="Gottwald, Leszek
and Kaźmierczak-Łukaszewicz, Sylwia
and Dukowicz, Andrzej
and Misiewicz, Piotr
and Ciałkowska-Rysz, Aleksandra",
pages="39--43",
url="https://www.termedia.pl/-Bone-metastases-from-breast-cancer-analysis-of-63-cases-,59,16529,1,1.html"
}