@Article{Arkuszewski2011,
journal="Gastroenterology Review/Przegląd Gastroenterologiczny",
issn="1895-5770",
volume="6",
number="4",
year="2011",
title="Surgical management of gastro-entero-pancreatic neuroendocrine tumours",
abstract="  Introduction  : Gastro-entero-pancreatic neuroendocrine tumours (GEP NET) are a large and differentiated group of neoplasms. Their clinical course can be various, which is conditioned, for instance, by the fact that some of these tumours are hormonally active.     Aim  : To analyse symptoms that can accompany neuroendocrine tumours of the digestive system and the circumstances in which these neoplasms are diagnosed; evaluation of the results of surgical management of patients who had GEP NET detected.     Material and methods  : Six patients (5 women and a 1 man) had gastro-entero-pancreatic neuroendocrine tumour diagnosed. Three female patients underwent scheduled surgical procedures due to pancreatic tumour. Two patients (a woman and a man) were operated on for acute appendicitis and carcinoid was found in the vermiform appendix after emergency appendectomy, whereas a woman who underwent cholecystectomy because of the signs of acute cholecystitis was suffering from neuroendocrine cancer of the gallbladder.     Results  : In 3 patients – a woman and a man after appendectomy and also a woman after surgical excision of pancreatic insulinoma – postoperative periods were uneventful. In the rest of patients postoperative complications occurred. A woman with neuroendocrine cancer of the gallbladder died 2 months after surgery. Five remaining living patients were in follow-up. Surgical treatment was confirmed to be curative in all of them.     Conclusions  : Gastro-entero-pancreatic neuroendocrine tumours are rare. Sometimes they are diagnosed preoperatively due to characteristic symptoms secondary to hormonal activity. However, gastro-entero-pancreatic neuroendocrine tumours are usually hormonally silent. Some of them are found in patients operated on because of an acute abdominal disease that can be caused by a neuroendocrine tumour. In the case of some GEP NET tumours which were resected, oncological treatment is not necessary.",
author="Arkuszewski, Piotr
and Pasieka, Zbigniew
and Kołomecki, Krzysztof
and Śmigielski, Jacek
and Kusiński, Michał
and Hedayati, Masoud
and Srebrzyński, Adam
and Kuzdak, Krzysztof",
pages="252--258",
doi="10.5114/pg.2011.24308",
url="http://dx.doi.org/10.5114/pg.2011.24308"
}