@Article{Kram2011,
journal="Polish Journal of Pathology",
issn="1233-9687",
volume="62",
number="3",
year="2011",
title="Morphometric distinction of signet-ring cell adenocarcinoma cells from foamy macrophages  in gastric endoscopic biopsies",
abstract="  Aims  : To distinguish signet-ring cancer cells from foamy macrophages in the small gastric endoscopic biopsies using objective morphometric measurements of nuclei.     Material and methods  : Using computerized image analysis, the mean nuclear area, length, breadth, perimeter and roundness were analyzed in histological sections of ten gastric endoscopic biopsies with signet-ring cell adenocarcinoma and four benign lesions with numerous foamy macrophages.      Results  : Nuclei of signet-ring cell adenocarcinoma were significantly bigger than nuclei of foamy macrophages. Mean nuclear area (34.25 μm 2  for carcinoma cells vs. 25.41 μm 2  for macrophages) and mean nuclear breadth (5.82 μm vs. 4.99 μm, respectively) differed significantly (P < 0.05), whereas the remaining parameters did not.     Conclusion  : Nuclear morphometry can distinguish foamy macrophages from signet-ring cell adenocarcinoma cells in endoscopic gastric biopsies.",
author="Kram, Andrzej
and Peychewa, Marieta
and Bachurska, Svetlana
and Domagala, Wenancjusz",
pages="145--147",
url="https://www.termedia.pl/Morphometric-distinction-of-signet-ring-cell-adenocarcinoma-cells-from-foamy-macrophages-in-gastric-endoscopic-biopsies,55,17722,1,1.html"
}