@Article{Krześlak2011,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="10",
number="6",
year="2011",
title="Diagnostic and prognostic value of O-linked N-acetylglucosamine transferase transferase in bladder 
neoplastic transformation in postmenopausal women",
abstract="  Aim of the study  : The aim of the study was to evaluate the usefulness of mRNA expression of O-GlcNAc transferase (OGT) for bladder neoplasm diagnosis and disease prognosis in postmenopausal women.    Material and methods  : OGT expression was measured by a real-time PCR assay in urine obtained from   52 postmenopausal women with bladder neoplasms and 37 healthy women. For the studied gene, cut-off, specificity and sensitivity were estimated.    Results:   For OGT, the cut-off value was 416.93, sensitivity 100% and specificity 88.9%. Expression of OGT was established in 36/46 (78.2%) urine specimens taken from women with bladder cancer and in 18/37 (48.6%) urine specimens from healthy women. There was no OGT expression in women with papillary urothelial neoplasms of low malignant potential (PUNLMP).    Conclusions  : Measurement of OGT mRNA level in urine samples obtained from postmenopausal women with urinary bladder cancer may be a useful marker of diagnosis and prognosis.",
author="Krześlak, Anna
and Wikosz, Jacek
and Forma, Ewa
and Różański, Waldemar
and Bryś, Magdalena
and Blewniewski, Mariusz
and Lipiński, Marek",
pages="432--435",
url="https://www.termedia.pl/-Diagnostic-and-prognostic-value-of-O-linked-N-acetylglucosamine-transferase-transferase-in-bladder-r-nneoplastic-transformation-in-postmenopausal-women-,4,18022,1,1.html"
}