@Article{Pająk2011,
journal="Polish Journal of Pathology",
issn="1233-9687",
volume="62",
number="4",
year="2011",
title="Serous neoplasms of the pancreas constitute a continuous spectrum of morphological patterns rather than distinct clinico-pathological variants. A study of 40 cases",
abstract="Serous neoplasms (SN) of the pancreas account for 1-2% of all pancreatic tumours. Six morphological variants of SN were previously recognized: serous microcystic (cyst)adenoma, serous macrocystic (cyst)adenoma, von Hippel-Lindau-associated serous cystic neoplasm, solid serous adenoma/neoplasm, mixed serous-neuroendocrine neoplasm and serous cystadenocarcinoma. It was recently postulated that SN shows a continuous spectrum of morphological patterns rather than distinct clinico-pathological subtypes. To address this issue, we performed a detailed review of 40 SN cases diagnosed at our institution between 1989 and 2011. We found 11 cases of serous microcystic (cyst)adenoma, 5 cases of serous macrocystic (cyst)adenoma, and a single case of von Hippel-Lindau-associated serous cystic neoplasm. Apart from that, we found 20 cases of SN which showed features of both microcystic and macrocystic (cyst)adenomas, 2 cases of small ‘incipient’ SN and a single case of a mixed microcystic and solid adenoma. In conclusion, we showed that ‘borderline’ lesions among SNs truly exist and are not rare. The reason for such a wide diversity of morphological patterns of SN remains unknown.",
author="Pająk, Jacek
and Liszka, Łukasz
and Mrowiec, Sławomir
and Zielińska-Pająk, Ewa
and Gołka, Dariusz
and Lampe, Paweł",
pages="206--217",
url="https://www.termedia.pl/Serous-neoplasms-of-the-pancreas-constitute-a-continuous-spectrum-of-morphological-patterns-rather-than-distinct-clinico-pathological-variants-A-study-of-40-cases,55,18073,1,1.html"
}