@Article{Pilichowska2012,
journal="Contemporary Oncology/Współczesna Onkologia",
issn="1428-2526",
volume="16",
number="2",
year="2012",
title="Treatment of stage I seminoma: 25 years of experience",
abstract=" Aim of the study:  To review management and outcomes in patients with stage I seminoma after orchidectomy.   Material and methods : Between 1979 and 2004 a total 292 patients with stage I seminoma were treated with adjuvant chemotherapy or radiotherapy or were placed on surveillance. Median age at diagnosis was 36 years (range 20-69), with median follow-up 76.5 months (range 11-294). Of the patients, 200 (68.5%) were treated with adjuvant chemotherapy, 72 (24.6%) were irradiated and 20 (6.8%) were placed on surveillance.    Results:  The probability of 5-year overall survival and relapse-free survival for the entire group was 100% and 95.1% respectively. The 5-year relapse-free survival for adjuvant chemotherapy was 97.2%, for radiotherapy 94.6%, and 31.4% for   the surveillance group. Of 24 (8.4%) patients who had relapse in lymph nodes and/or internal organs, 14/20 patients were in the surveillance group. All patients who had a relapse were salvaged successfully with chemotherapy. The toxicity of chemotherapy and radiotherapy was acceptable. No severe reactions were observed.   Conclusion : Our results confirm the excellent prognosis for patients with stage I seminoma after orchidectomy treated with adjuvant chemotherapy or radiotherapy. The high rate of relapse in our surveillance group suggests the necessity of adjuvant treatment.",
author="Pilichowska, Małgorzata
and Pęczkowski, Piotr
and Rosińska-Okrasa, Dorota
and Trzaska, Barbara
and Skowrońska-Gardas, Anna
and Demkow, Tomasz",
pages="104--107",
doi="10.5114/wo.2012.28788",
url="http://dx.doi.org/10.5114/wo.2012.28788"
}