@Article{Krześlak2012,
journal="Menopause Review/Przegląd Menopauzalny",
issn="1643-8876",
volume="11",
number="3",
year="2012",
title="Diagnostic value of glucose transporter 1 and 3 (GLUT1 and GLUT3) mRNA level
in postmenopausal women with urinary bladder cancer",
abstract=" Purpose : The aim of the study was to evaluate the usefulness of glucose transporters (GLUT1 and GLUT3) mRNA level for bladder cancer diagnosis in postmenopausal women.    Material and methods : Glucose transporters expression was measured by a real-time polymerase chain reaction (real-time PCR) assay in urine obtained from 46 postmenopausal women with bladder cancer and 37 healthy women.   Results : GLUT1 expression was found in urine of both healthy women (74%) and bladder cancer patients (82%). GLUT3 expression was not detected in urine of healthy persons but it was found in 62% of bladder cancer samples. A positive expression of poorly differentiated bladder cancers (G2, G3) showed a significantly higher GLUT1 expression than G1 tumors. Similarly, GLUT 3 transcript level was significantly higher in G2 and G3 in comparison to G1 bladder cancers. Analogous results were obtained for both genes in relation to the clinical stage (ta-T1 vs. T2-T4). There was no relationship between the expression of studied genes and recurrence.    Conclusions : Analysis of the glucose transporters expression in the urine of postmenopausal women with bladder cancer appears to be a useful diagnostic indicator of the disease.",
author="Krześlak, Anna
and Jóźwiak, Paweł
and Forma, Ewa
and Bryś, Magdalena
and Woźniak, Paweł
and Wikosz, Jacek
and Lipiński, Marek
and Różański, Waldemar",
pages="178--182",
url="https://www.termedia.pl/Diagnostic-value-of-glucose-transporter-1-and-3-GLUT1-and-GLUT3-mRNA-level-r-nin-postmenopausal-women-with-urinary-bladder-cancer,4,18950,1,1.html"
}