@Article{Kępka2012,
journal="Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej",
issn="1734-9338",
volume="8",
number="3",
year="2012",
title="Original paperDiagnostic accuracy of dual-source coronary computed tomography angiography in patients after bypass grafting",
abstract=" Aim:  To determine the diagnostic accuracy of dual-source (DS) coronary computed tomography angiography (CCTA) with improved temporal resolution in a population of symptomatic patients after coronary artery bypass grafting (CABG) compared to invasive coronary angiography (ICA).    Material and methods:  Ninety (74 male, mean age: 68 ±9 years) symptomatic post-CABG patients from the prospective ANIN Coronary Computed Tomography Angiography Registry who underwent both DS-CCTA and ICA for suspected graft disease were included in the analysis. A total of 202 grafts (67 arterial grafts, 135 venous grafts) and 1,105 segments in 360 native coronary arteries  1.5 mm in diameter were evaluated for the presence of significant stenosis, defined as  50% decrease in vessel diameter. Results were compared with ICA as the standard of reference.   Results : Sensitivity, specificity, and positive and negative predictive values of DS-CCTA for the detection of significant lesions in bypass grafts were 99%, 96%, 94%, and 99%, respectively. Segment-by-segment analysis of native coronary arteries for the detection of obstructive disease yielded sensitivity of 91% with specificity of 92%. If analysis was restricted to non-grafted and distal runoff segments, sensitivity and specificity were 88% and 96%, respectively. The presence of coronary calcium deposits was associated with a significant decrease in diagnostic accuracy of DS-CCTA.    Conclusions : The DS-CCTA allows reliable evaluation of suspected graft disease in symptomatic post-CABG patients, whereas ICA is still required for the assessment of significant stenoses in native coronary circulation.",
author="Kępka, Cezary
and Opolski, Maksymilian
and Kruk, Mariusz
and Pręgowski, Jerzy
and Kowalewska, Anna
and Wilkowska, Paulina
and Dzielińska, Zofia
and Karcz, Maciej
and Rużyłło, Witold
and Demkow, Marcin",
pages="183--192",
doi="10.5114/pwki.2012.30396",
url="http://dx.doi.org/10.5114/pwki.2012.30396"
}